Formulasi Sediaan Krim Menggunakan Kolagen Tulang Ikan Patin (Pangasius sp.) sebagai Anti Aging


  • Sudewi Sudewi * Mail Universitas Tjut Nyak Dhien, Medan, Indonesia
  • Nilsya Febrika Zebua Universitas Tjut Nyak Dhien, Medan, Indonesia
  • Shelva Filiana Sari Universitas Tjut Nyak Dhien, Medan, Indonesia
  • (*) Corresponding Author
Keywords: Patin Fish; Bone; Collagen; Cream; Anti Aging

Abstract

Patin fish (Pangasius sp.) is a fish that has been cultivated by many people because it has a high content of omega 3. People consume patin fish meat as a source of protein, while patin fish bones are only disposed of as waste. Collagen is a protein derivative that has the effect of maintaining skin elasticity. This study aims to determine whether the patin fish bones contain collagen and is there an influence of the use of anti-aging collagen patin fish bone cream on the results of changes in facial skin care. Collagen characterization using infrared spectrophotometry and formulated into cream preparations with concentrations of 1%, 1,5%, 2,5%, 3,5% and evaluation of preparations include homogeneity test, pH measurement, emulsion type determination test, stability test, skin irritation to volunteers and anti-aging effectiveness test. The results showed that patin fish bones contained collagen at wave numbers 3250-3350 cm-1 and 1260-1630 cm-1 which indicated the presence of amine and amide groups. The use of patin fish collagen cream affects the changes in texture, wrinkles, moisture, blemishes and pores become smoother. The best formulation is the formula that contains 3,5% of patin fish bone collagen

Downloads

Download data is not yet available.

References

Aramo.2012. Skin and Hair Diagnosis System. Sungna: Aram Huvis Korea Ltd. P : 1-10.

Ditjen POM. 1995. Farmakope Indonesia. Edisi IV. Jakarta: Departemen Kesehatan RI. Halaman 311.

Fauzi, A.R., dan Nurmalina, R. 2012. Merawat Kulit dan Wajah. Jakarta: PT Elex Media Komputindo. Halaman 60, 171-173.

Hashim, P., Ridzwan M. S. M dan Bakar J. 2014. Isolation and Characterization of Collagen from Chicken Feet. Engineering and Technology International Journal of Bioengineering and Life Sciences. 8(3):250.

Jaelani. 2009. Ensiklopedi Kosmetika Nabati. Jakarta: Pustaka Populer Obor. Halaman 153-155.

Kittiphattanabawon, P., Benjakul, S., Visessanguan, W., Nagai, T dan Tanaka, M. 2005. Characterisation of Acid-Soluble Collagen from Skin and Bone of Bigeye Snapper (Priacanthus tayenus). Journal Food Chemistry. Thailand: 89(3): 363.

Kong, J dan Yu, S. 2007. Fourier Transform Infrared Spectroscopic Analysis of Protein Secondary Structures. Journal Acta Biochimica et Biophysica Sinica. Shanghai: 39(8): 549.

Kordi, M. G. H. 2005. Budidaya Ikan Patin Biologi, Pembenihan dan Pembesaran. Yogyakarta: Yayasan Pustaka Nusatama. Halaman 87.

Li, Z., Wang, B., Chi, C., Zhang, Q., Gong, Y., Tang, J., Luo, H dan Ding, G. 2013. Isolation and Characterization of Acid Soluble Collagens and Pepsin Soluble Collagens from The Skin and Bone of Spanish Mackerel (Scomberomorous niphonius). Journal Food Hydrocolloids. Zhoushan:31(1): 103.

Nazliniwaty, Karsono, Zebua, N.F. 2016. Antioxidant activity and antiaging gel formulation grapefruit peel (Citrus maxima Merr.) ethanolic extract. Der Pharmacia Lettre. 8(20):84-94.

Prianto. J. 2014. Cantik Panduan Lengkap Merawat Kulit Wajah. Jakarta: PT Gramedia Pustaka Utama. Halaman 60, 118-145.

Pringgandini, L. A., Indarti, G. Y., Melinda dan Sari, M. 2018. Efektifitas Spray Nanokolagen Limbah Sisik Ikan Mas (Cyprinus carpio) untuk Mempercepat Proses Penyembuhan Luka Insisi. Laporan Penelitian. Departemen Ilmu Kesehatan Gigi Masyarakat, Fakultas Kedokteran Gigi, Universitas Muhammadiyah Surakarta. Halaman 116.

Rahim, F., Aria, M., Aji, N.P. 2011. Formulasi Krim Ekstrak Etanol Daun Ubi Jalar (Ipomoeaea batatas L.) untuk Pengobatan Luka Bakar. Jurnal Scientia. 1(1):21-26.

Sonave, A. E., Koli, J. M., Patange, S. B., Naik, S. D and Mohite, A. S. 2018. Isolation of Acid and Pepsin Soluble Collagens from The Skin of Indian Mackerel (Rastrellinger kanugarta) (Cuvier, 1817). Journal of Enromology and Zoologi Studies. 6(2): 2509.

Veeruraj, A., Arumugam, M dan Balasubramanian, T. 2013. Isolation and Characterization of Thermostable Collagen from The Marine eel-fish (Evenchelys macrura). Journal Process Biochemistry. India: 48(1): 1592.

Young, A. 1972. Practical Cosmetic Science. London: Mills and Boon Limited. Halaman 51.


Bila bermanfaat silahkan share artikel ini

Berikan Komentar Anda terhadap artikel Formulasi Sediaan Krim Menggunakan Kolagen Tulang Ikan Patin (Pangasius sp.) sebagai Anti Aging

Dimensions Badge
Article History
Submitted: 2020-05-08
Published: 2020-06-30
Abstract View: 1948 times
PDF Download: 2286 times
Section
Articles

Most read articles by the same author(s)