Uji Efektivitas Ekstrak Etanol Daun Ketapang (Terminalia cattapa L.) Terhadap Bakteri Patogen
-
Muharni Saputri
*
Universitas Tjut Nyak Dhien, Medan,
Indonesia
- Vriezka Mierza Universitas Tjut Nyak Dhien, Medan, Indonesia
- Nilsya Febrika Zebua Universitas Tjut Nyak Dhien, Medan, Indonesia
- M Ridho Pangestu Panjaitan Universitas Tjut Nyak Dhien, Medan, Indonesia (*) Corresponding Author
Abstract
Antiba Antibacterials work by preventing and managing the growth of pathogenic bacteria. The goal of controlling bacterial growth is to stop the spread of infection. Basically, people use synthetic drugs in antibacterial prevention but often there is a lot of resistance in the human body that can cause adverse effects. The active ingredients in ketapang leaves have the potential to act as natural antibiotics and antibacterials to combat antibiotic resistance. To determine the antibacterial effectiveness of these chemical compounds against bacteria Pseudomonas aeruginosa, Demacoccus nishinomiyaensi, Stapylococcus epidermidis and Micrococcus luteus, a study was conducted with the aim of knowing the content of chemical compounds contained in ketapang leaves based on maceration results. This study uses an experimental descriptive method with Ketapang leaf test material (Terminalia cattapa L.) This research stage includes making simplisia, maceration extraction using ethanol solvent, antibacterial activity test agar well diffusion method and analysis of chemical compound components by phytochemical screening.The results of drying fresh ketapang leaves produce as much as 1.6 kg of simplisia, and when 300 grams of ketapang leaf simplisia is macerated using ethanol pro analysis, 1.5 kg of simplisia is obtained. The ethanol extract from the maceration of ketapang leaves has antibacterial activity as shown by the inhibition of Pseudomonas aeruginosa bacteria by 18.38 mm, Dermacoccus nishinomiyaensis bacteria by 23.05 mm, Staphylococcus epidermidis bacteria by 18.71 mm, and Micrococcus luteus bacteria by 20.71 mm. After screening the ethanol extract of ketapang leaves, triterpenoid components, anthraquinone glycosides, saponins, and tannins were found. Flavonoid compounds were also found.
Downloads
References
Adi Saputra, Tafdhila, & Mayaranti Wilsya. (2021). AKTIVITAS ANTIJAMUR EKSTRAK ETANOL BUNGA KETEPENG CINA (Senna alata l) TERHADAP JAMUR Candida albicans. Jurnal Kesehatan : Jurnal Ilmiah Multi Sciences, 11(2), 79–85. https://doi.org/10.52395/jkjims.v11i2.326
Anggraeni, A., & Triajie, H. (2021). UJI KEMAMPUAN BAKTERI ( Pseudomonas aeruginosa) DALAM PROSES BIODEGRADASI PENCEMARAN LOGAM BERAT TIMBAL (Pb), DI PERAIRAN TIMUR KAMAL KABUPATEN BANGKALAN. Juvenil:Jurnal Ilmiah Kelautan Dan Perikanan, 2(3), 176–185. https://doi.org/10.21107/juvenil.v2i3.11754
Asali, A., Inwar, A. I., Alim. M, I., Tiffani, I., & Rahmadani, A. F. (2023). Effectiveness Test of Ginger Extract (Zingiber officinale) on the Growth Inhibition Zone of Escherichia Coli Bacteria. Era Sains : Journal of Science, Engineering and Information Systems Research, 1(4), 15–20.
Hasanah, F., Saputri, M., Siahaan, D. N., Kusuma, P. A., & Matondang, S. R. R. (2023). Uji Antidiare Ekstrak Etanol Daun Matoa (Pometia pinnata) Terhadap Mencit Jantan Diinduksi Oleum Ricini. Journal of Pharmaceutical and Health Research, 4(2), 342–348. https://doi.org/10.47065/jharma.v4i2.3620
Lady Yunita Handoyo, D., & Pranoto, M. E. (2020). Pengaruh Variasi Suhu Pengeringan Terhadap Pembuatan Simplisia Daun Mimba (Azadirachta Indica). Jurnal Farmasi Tinctura, 1(2), 45–54. https://doi.org/10.35316/tinctura.v1i2.988
Maya Puspitasari, Firman Rezaldi, E.Egriana Handayani, & Dedeh Jubaedah. (2022). KEMAMPUAN BUNGA TELANG (Clitoria ternatea L) SEBAGAI ANTIMIKROBA (Listeria monocytogenes, Staphylococcus hominis, Trycophyton mentagrophytes, dan Trycophyton rubrum) MELALUI METODE BIOTEKNOLOGI FERMENTASI KOMBUCHA. Jurnal Medical Laboratory, 1(2), 1–10. https://doi.org/10.57213/medlab.v1i2.36
Muldianah, D., Nurdimayanthi, D. A., Rahmawati, D. S., & Fadhilah, H. (2021). Teknik Isolasi dan Identifikasi Senyawa Glikosida dari Berbagai Tanaman. PharmaCine : Journal of Pharmacy, Medical and Health Science, 2(1), 11–21. https://doi.org/10.35706/pc.v2i1.5577
Nasri, N., Kaban, V. E., Syahputra, H. D., & Satria, D. (2022). Aktivitas Antibakteri Ekstrak Etanol Daun Alpukat (Persea americana Mill) Terhadap Escherichia coli, Salmonella typhi, dan Pseudomonas aeruginosa. Herbal Medicine Journal, 5(1), 13–19. https://doi.org/10.58996/hmj.v5i1.37
Putriani, K., Sugara, B., Studi, P., Keperawatan, D., Hang, S., & Tanjung, T. (2024). Aktivitas Antibakteri Ekstrak Daun Ketapang ( Terminalia Catappa L .) Terhadap Staphylococcus Aureus. INNOVATIVE: Journal Of Social Science Research, 4(7 mm), 4178–4187.
Rinawati, Tirta, I., Budhiarti, Aulia Eka Putri, D., & Kurniaty, I. (2022). Pengaruh Konsentrasi Ekstrak Kental Daun Kanyere (Bridelia Monoica (L). Merr) Sebagai Antiinflamasi Dalam Sediaan Gel Luka Bakar. Jurnal Teknologi, 14(1), 80–90. https://dx.doi.org/10.24853/jurtek.14.1.79-90
Rosmania, R., & Yuniar, Y. (2021). Pengaruh Waktu Penyimpanan Inokulum Escherichia coli dan Staphilococcus aureus Pada Suhu Dingin Terhadap Jumlah Sel Bakteri di Laboratorium Mikrobiologi. Jurnal Penelitian Sains, 23(3), 117. https://doi.org/10.56064/jps.v23i3.624
Saptowo, A., Supriningrum, R., & Supomo, S. (2022). UJI AKTIVITAS ANTIBAKTERI EKSTRAK KULIT BATANG SEKILANG (Embeliaborneensis Scheff) TERHADAP BAKTERI Propionibacterium acnes dan Staphylococcus epidermidis. Al-Ulum: Jurnal Sains Dan Teknologi, 7(2), 93. https://doi.org/10.31602/ajst.v7i2.6331
Saputri, M., Febriani, Y., & Olyvia putri, O. putri. (2023). Formulasi Dan Uji Efektivitas Sediaan Salep Ekstrak Etanol Daun Sintrong (Crassocephalum crepidioides (Benth.) S.Moore) Terhadap Penyembuhan Luka Bakar Pada Marmut Jantan (Cavia porcellus). Journal of Pharmaceutical and Sciences, 6(2), 598–606. https://doi.org/10.36490/journal-jps.com.v6i2.52
Saputri, M., & Mierza, V. (2020). Aktivitas Antibakteri Sediaan Gel dari Fraksi Aktif Daun Sintrong (Crassocephalum Crepidioides (Benth) S Moore). Journal of Pharmaceutical and Health Research, 1(3), 72–76. https://doi.org/10.47065/jharma.v1i3.595
Saputri, M., Mierza, V., & Putri, N. (2022). Antimicrobic Activity of IPPU Padang (Ammannia octandra L.f.) Leaves Ethanol Extract against Skin Pathogenic Microbials. Journal of Fundamental and Applied Pharmaceutical Science, 3(1), progress. https://doi.org/10.18196/jfaps.v2i2.13505
Siva, S. F., Yurdhika Habsari, K., Risnawati, L., Putri Firdhiana, W., Rahma Pertiwi, A., Rita Sulistya Dewi, E., & Nurwahyunani, A. (2023). Uji Daya Hambat Pada Tanaman Ketapang (Terminalia catappa L.) dan Manggis (Garcinia Mangostana) Terhadap Mikroorganisme Patogen. Cross-Border, 6(2), 1146–1159.
Sudewi, S., Zebua, N. F., Dahra, A., & Pasaribu, I. (2024). Pemanfaatan Bahan Alam Dalam Sediaan Lotion Sebagai Pelembab Kulit Dengan Menggunakan Spektrofotometri Uv-Vis. Jambura Journal of Health Sciences and Research, 6(2), 136–145. https://doi.org/10.35971/jjhsr.v6i2.21917
Sumardi, S., Zebua, N. F., Mierza, V., Arafah, R. M., Qhairunnisa, Q., & Amalia, R. (2023). Profil Noda Ekstrak Kloroform : Metanol (2:1) dan Aktivitas Bslt Kulit Batang Nyirih (Xylocarpus Granatum). Journal of Pharmaceutical and Health Research, 4(2), 326–332. https://doi.org/10.47065/jharma.v4i2.3678
Zebua, N. F., Sudewi, Siti Arum Widiyanti, Muflihah Fujiko, Nurul Karimah, Supran Hidayat, & Rahma Yulia. (2022). Formulation and Testing of Antioxidant Cream Preparation of Ethanol Extract of Cikala Fruit (Etlingera elatior (Jack) R. M. Sm) as a Skin Moisturizer. Jurnal Indah Sains Dan Klinis, 3(2), 34–40. https://doi.org/10.52622/jisk.v3i2.63
Bila bermanfaat silahkan share artikel ini
Berikan Komentar Anda terhadap artikel Uji Efektivitas Ekstrak Etanol Daun Ketapang (Terminalia cattapa L.) Terhadap Bakteri Patogen
Pages: 64-70
Copyright (c) 2024 Muharni Saputri
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under Creative Commons Attribution 4.0 International License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (Refer to The Effect of Open Access).
