Clinical Review of Safety and Outcomes in Minimally Invasive Thyroid Surgery
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Rudi Haris Munandar
*
Universitas Riau, Pekanbaru,
Indonesia
(*) Corresponding Author
Abstract
Thyroid cancer is one of the most common endocrine malignancies, with surgery remaining the cornerstone of its management. Conventional open thyroidectomy, although oncologically effective, is often associated with postoperative morbidity, prolonged recovery, and cosmetic concerns. These limitations have driven the development of minimally invasive thyroid surgery (MITS) as an alternative approach. This study aims to clinically review the safety, effectiveness, and postoperative outcomes of MITS in the management of thyroid cancer. A clinical review was conducted by analyzing relevant peer reviewed studies published in international databases, focusing on surgical safety, oncological effectiveness, and postoperative recovery outcomes. The results indicate that MITS demonstrates a safety profile comparable to open thyroidectomy, with no significant increase in major complications such as hypoparathyroidism or recurrent laryngeal nerve injury. Oncological outcomes, including tumor control and recurrence rates, were equivalent in selected low to intermediate risk patients. Moreover, MITS consistently showed superior postoperative outcomes, including reduced pain, shorter hospital stays, faster recovery, and higher cosmetic satisfaction. These findings support MITS as a safe and effective surgical option within patient centered thyroid cancer management.
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References
Agcaoglu, O., Sucu, S., Toprak, S., & Tezelman, S. (2024). Techniques for thyroidectomy and functional neck dissection. Journal of Clinical Medicine, 13(7).
Avram, A. M., Zukotynski, K., Nadel, H. R., & Giovanella, L. (2022). Management of differentiated thyroid cancer: The standard of care. Journal of Nuclear Medicine, 63(2), 189–195.
Branca, J. J. V., Bruschi, A. L., Pilia, A. M., Carrino, D., Guarnieri, G., & Gulisano, M., et al. (2022). The thyroid gland: A revision study on its vascularization and surgical implications. Medicina, 58(1).
Brandler, T. C., Zhou, F., Liu, C. Z., Serrano, A., Sun, W., Nikiforov, Y. E., et al. (2023). Molecular profiles of noninvasive, minimally invasive, and invasive follicular patterned thyroid neoplasms with papillary nuclear features. Thyroid, 33(6), 715–723.
Chorti, A., Bontinis, V., Tzikos, G., Bontinis, A., Ioannidis, A., Michalopoulos, A., et al. (2023). Minimally invasive treatments of benign thyroid nodules: A network meta analysis of short term outcomes. Thyroid, 33(8), 950–964.
Chou, R., Dana, T., Haymart, M., Leung, A. M., Tufano, R. P., & Sosa, J. A., et al. (2022). Active surveillance versus thyroid surgery for differentiated thyroid cancer: A systematic review. Thyroid, 32(4), 351–367.
Creswell, J. W., & Creswell, J. D. (2018). Mixed methods procedures. In Research design: Qualitative, quantitative, and mixed methods approaches (pp. 418). SAGE Publications.
Creswell, J. W., & Creswell, J. D. (2023). Research design: Qualitative, quantitative, and mixed methods approaches (5th ed., pp. 37–60). SAGE Publications.
Garo, M. L., Campennì, A., Petranovic Ovcaricek, P., D’Aurizio, F., & Giovanella, L. (2023). Evolution of thyroid cancer biomarkers: From laboratory test to clinical management. Clinical Chemistry and Laboratory Medicine, 61(5), 935–945.
Ghai, S., Goldstein, D. P., & Sawka, A. M. (2024). Ultrasound imaging in active surveillance of small, low risk papillary thyroid cancer. Korean Journal of Radiology, 25(8), 749–755.
Haddaway, N. R., Page, M. J., Pritchard, C. C., & McGuinness, L. A. (2022). PRISMA2020: An R package and Shiny app for producing PRISMA 2020 compliant flow diagrams. Campbell Systematic Reviews, 18(2), e1230. https://doi.org/10.1002/cl2.1230
Jasim, S., Patel, K. N., Randolph, G., Adams, S., Cesareo, R., Condon, E., et al. (2022). The clinical utility of minimally invasive interventional procedures in the management of benign and malignant thyroid lesions. Endocrine Practice, 28(4), 433–448. https://doi.org/10.1016/j.eprac.2022.02.011
Kuo, T. C., Chen, K. Y., Lai, C. W., Lin, M. T., Chang, C. H., & Wu, M. H. (2025). Transoral endoscopic and minimally invasive thyroidectomy. JAMA Surgery, 160(11), 1203–1210.
Ludwig, B., Ludwig, M., Dziekiewicz, A., Mikuła, A., Cisek, J., Biernat, S., et al. (2023). Modern surgical techniques of thyroidectomy and advances in the prevention and treatment of perioperative complications. Cancers, 15(11).
Machens, A., Lorenz, K., Brandenburg, T., Führer, D., Weber, F., & Dralle, H. (2024). Latest progress in risk adapted surgery for medullary thyroid cancer. Cancers, 16(5).
Mulita, F., Verras, G. I., Dafnomili, V. D., Tchabashvili, L., Perdikaris, I., Bousis, D., et al. (2022). Thyroidectomy for differentiated thyroid carcinoma and early postoperative complications: A 6 year single centre retrospective study. Chirurgia, 117(5), 556–562.
Papini, E., Guglielmi, R., Novizio, R., Pontecorvi, A., & Durante, C. (2024). Management of low risk papillary thyroid cancer: Minimally invasive treatments dictate a further paradigm shift? Endocrine, 85(2), 584–592. https://doi.org/10.1007/s12020 024 03864 7
Pace Asciak, P., Russell, J. O., & Tufano, R. P. (2022). The treatment of thyroid cancer with radiofrequency ablation. Techniques in Vascular and Interventional Radiology, 25(2), 100825. https://doi.org/10.1016/j.tvir.2022.100825
Pace Asciak, P., Russell, J. O., & Tufano, R. P. (2023). Improving quality of life in patients with differentiated thyroid cancer. Frontiers in Oncology, 13, 1–7.
Park, J. O., Kim, J. H., Joo, Y. H., Kim, S. Y., Kim, G. J., Kim, H. B., et al. (2023). Guideline for the surgical management of locally invasive differentiated thyroid cancer. Clinical and Experimental Otorhinolaryngology, 16(1), 1–19.
Sandy, J. L., Titmuss, A., Hameed, S., Cho, Y. H., Sandler, G., & Benitez Aguirre, P. (2022). Thyroid nodules in children and adolescents: Investigation and management. Journal of Paediatrics and Child Health, 58(12), 2163–2168.
Scheller, B., Culié, D., Poissonnet, G., Dassonville, O., D’Andréa, G., & Bozec, A. (2023). Recent advances in the surgical management of thyroid cancer. Current Oncology, 30(5), 4787–4804.
Shonka, D. C., Ho, A., Chintakuntlawar, A. V., Geiger, J. L., Park, J. C., Seetharamu, N., et al. (2022). Consensus statement on mutational testing in thyroid cancer. Head & Neck, 44(6), 1277–1300.
Sugiyono. (2021). Metode penelitian kuantitatif, kualitatif, dan R&D. Alfabeta.
van Houten, P., Netea Maier, R. T., & Smit, J. W. (2023). Differentiated thyroid carcinoma: An update. Best Practice & Research Clinical Endocrinology & Metabolism, 37(1), 101687. https://doi.org/10.1016/j.beem.2022.101687
Zhao, Z. L., Wang, S. R., Dong, G., Liu, Y., He, J. F., Shi, L. L., et al. (2024). Microwave ablation versus surgical resection for US detected multifocal T1N0M0 papillary thyroid carcinoma: A 10 center study. Radiology, 311(1), 1–9.
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