Formulasi dan Uji Aktivitas Sediaan Masker Gel Peel Off Ekstrak Etanol 70% Daun Rambutan (Nephelium Lappaceum L.) Terhadap Propionibacterium Acnes
-
Rahmawida Putri
*
Sekolah Tinggi Farmasi Muhammadiyah Tangerang, Tangerang,
Indonesia
- Jaka Supriyanta Sekolah Tinggi Farmasi Muhammadiyah Tangerang, Tangerang, Indonesia
- Dwi Afriliyani Adhil Sekolah Tinggi Farmasi Muhammadiyah Tangerang, Tangerang, Indonesia (*) Corresponding Author
Abstract
Rambutan Leaves (Nephelium Lappaceum L.) one of the plants that contain, alkaloids, flavonoids, tannins and saponins have antibacterial activity against Propionibacterium acnes which is a bacterium that causes acne. Rambutan leaf extract can be formulated to facilitate its use, one of which is in the form of a gel such as a peel off mask. This study aims to determine the characteristics of peel off mask preparations and to determine the antibacterial activity of ethanol extract 70% rambutan leaves (Nephelium Lappaceum L.) Peel off gel mask preparations 70% ethanol extract rambutan leaves (Nephelium Lappaceum L.) formulated into 4 formulas with a variety of extract concentrations, namely F1 (0%), F2 (10%), F3 (15%), F4 (20%). Physical evaluation tests which include: organoleptic, homogeneity, pH, viscosity, dry time, spreadability, adhesion, and irritation. And the antibacterial activity test was carried out against Propionibacterium acnes bacteria using the well method. The results showed that the physical evaluation was said to be good to meet the requirements. Antibacterial test results of gel peel off mask preparation of 70% ethanol extract of rambutan leaves (Nephelium Lappaceum L.) showed the existence of antibacterial activity against Propionibacterium acnes bacteria inhibition was the best at the concentration of F4 (20%) with an average diameter of 10.03 mm. One way ANOVA analiysis result showed that there wewre significant differences in each formula group (p<0,05).
Downloads
References
Ardini, D., & Rahayu, P. (2019). Studi Variasi Gelling Agent PVA (Propil Vinil Alkohol) pada Formulasi Masker Peel-Off Ekstrak Lidah Buaya (Aloe vera) sebagai Anti Jerawat. Jurnal Kesehatan, 10(2), 245-251.
Ariani, Li. W. dan Wigati, D. (2016). Formulasi Masker Gel Peel-Off Ekstrak Etanol Kulit Buah Jeruk Manis (Citrus sinensis (L.) Osbeck) sebagai Obat Jerawat. Media Farmasi Indonesia, 11(2), hal. 1084–1092.
Eddy, S., Dahlianah, I., Rizal, S., & Kartika, T. (2018). PENYULUHAN MENGGALI POTENSI TANAMAN OBAT PADA SMAN 1 RAMBUTAN BANYUASIN SUMATERA SELATAN. Jurnal Pengabdian Masyarakat Bumi Raflesia, 1(1).
Handayani, S., Wirasutisna, K. R., & Insanu, M. (2017). Penapisan Fitokimia dan Karakterisasi Simplisia Daun Jambu Mawar (Syzygium jambos alston). Jurnal. JK FIK UINAM. Vol. 5 No. 3. Hal: 174-183.
Hariana, A. (2006). Tumbuhan Obat dan khasiatnya.pdf. seri 3. Depok: Penebar Swadaya.
Hernanz, D., V. Gallo, & A.N.F. Recamales. (2008). Comparison of The Effectiveness of Solid-Phase and Ultrasound-Mediated Liquid–Liquid Extractions to Determine the Volatile Compounds of Wine. Talanta, 76(4): 929-935.
Istiqomah, N. dan Metha Anung A. (2018). Pengaruh Penggunaan Hidroksi Propil Metil Celulosa (HPMC) Sebagai Gelling Agent Terhadap Sifat Fisik Masker Peel Off Ekstrak Daun Sirih (Piper betle L.) Jurnal PENA Vol.32 No.2. Fakultas Farmasi Universitas Pekalongan.
Maharani A. (2015). Penyakit Kulit Perawatan, Pencegahan dan Pengobatan. Pustaka Baru Press. Yogyakarta.
Movita, T. (2013). Acne vulgaris. Continuing Medical Education, 40(4), 269-272.
Novianti, Santi. (2016). Pengembangan Formulasi dan Uji Evaluasi Fisik Sediaan Masker Gel Dari Ekstrak Etanol 70% Daun Bayam Merah (Amaranthus tricolor L.) Skripsi. Sekolah Tinggi Farmasi Muhammadiyah Tangerang.
Pramiastuti, O., Larasati, L., Firsty, G. R., Nurfauziah, A., & Alquraisi, R. H. A. (2019, December). Masker Peel-Off Anti Jerawat Kombinasi Perasan Buah Tomat (Solanum lycopersicum L. Var. cucurbita) dan Daun Sirih (Piper betle L.). In Prosiding Seminar Nasional LPPM UMP (pp. 132-139).
Putrajaya, F., Hasanah, N., & Kurlya, A. (2019). Daya Hambat Ekstrak Etanol Daun Suruhan (Peperomia pellucida l.) Terhadap Pertumbuhan Bakteri Penyebab Jerawat (Propionibacterium acnes) Dengan Metode Sumur Agar. Edu Masda Journal, 3(2), 123-140.
Sarlina, S., Razak, A. R., & Tandah, M. R. (2017). Uji Aktivitas Antibakteri Sediaan Gel Ekstrak Daun Sereh (Cymbopogon nardus L. Rendle) terhadap Bakteri Staphylococcus aureus Penyebab Jerawat. Jurnal Farmasi Galenika (Galenika Journal of Pharmacy)(e-Journal), 3(2), 143-149.
Wasitatmadja, S.M. (1997). Penentuan Ilmu Kosmetik Medika. Jakarta : Penerbit UI-Press. Hal :3-5 ; 11-15,; 58-60.
Wijaya, H., Wibowo, M. A. dan Rahmayanti, S. (2015). Uji Aktivitas Antibakteri Ekstrak Etanol Daun Mangga Bacang (Mangifera foetide L) Terhadap Pertumbuhan Shigella flexneri Secara In Vitro. Skripsi. Sekolah Tinggi Farmasi Muhammadiyah Tangerang.
Bila bermanfaat silahkan share artikel ini
Berikan Komentar Anda terhadap artikel Formulasi dan Uji Aktivitas Sediaan Masker Gel Peel Off Ekstrak Etanol 70% Daun Rambutan (Nephelium Lappaceum L.) Terhadap Propionibacterium Acnes
Pages: 12-20
Copyright (c) 2021 Rahmawida Putri, Jaka Supriyanta, Dwi Afriliyani Adhil
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under Creative Commons Attribution 4.0 International License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (Refer to The Effect of Open Access).
