Optimization of HPMC Aand Carbopol 940 Bases in the Formulation of Red Beet (Beta vulgaris L.) Gel Preparations as Hair Dye


  • Putri Tri Hartini * Mail Institut Kesehatan Helvetia, Medan, Indonesia
  • Ziza Putri Aisyia Fauzi Universitas Muslim Nusantara Al-Washliyah, Medan, Indonesia
  • Dinda Sari Utami Universitas Muslim Nusantara Al-Washliyah, Medan, Indonesia
  • Sry Ulina Karo-Karo Institut Kesehatan Helvetia, Medan, Indonesia
  • Cut Intan Annisa Puteri Universitas Muslim Nusantara Al-Washliyah, Medan, Indonesia
  • (*) Corresponding Author
Keywords: Carbopol 940 Base; Hair Dye Gel; HPMC; Red Beet Juice

Abstract

Red beet (Beta vulgaris L.) is grass-shaped plant with short stems. Betacyianine is a red or purplish red pigment, while the betaxantin pigment has yellow colour and when diluted in water will form a red solution. This study aims to formulate hair dye gel with red beet juiceas colorant, evaluate the coloring capacity of the gel, and evaluate the stability of the formulation. 114.43 grams red beet juice was obtained using juicer, with yield percentage 55.76%. Phytochemical screening indicated alkaloid, tannin, flavonoid and saponin content. Hair dye gel is formulated in three different concentrations, F1 (10%), F2 (20%), F3 (30%) using combination of Carbopol 940 (0.5%) and HPMC (1%) as gel base. Hair dye gel obtained has beet distinctive smell. Evaluation results for the three-formulation showed that the color changed in all formulas. Color changing is influenced by pH degree of the formulation and temperature. The original color of the preparation only stable for 5 days, then the color changed due to oxidation at room temperature. Stability evaluation was conducted using Cycling Test method for 6 cycles in 12 days. All formula showed discoloration after 6 cycles from purple to brownish and they also showed viscosity change, F1 13673,34 cPs; F2 11826,67 cPs; dan F3 10673,34 cPs.

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References

Andini, T., Yusriadi, Y., & Yuliet, Y. (2017). Optimasi pembentuk film polivinil alkohol dan humektan propilen glikol pada formula masker gel peel off sari buah labu kuning (Cucurbita moschata duchesne) sebagai antioksidan. Jurnal Farmasi Galenika (Galenika Journal of Pharmacy)(e-Journal), 3(2), 165–173.

Bouslamti, M., Elrherabi, A., Loukili, E. H., Noman, O. M., Mothana, R. A., Ibrahim, M. N., Abdnim, R., Slighoua, M., Bouhrim, M., & Bnouham, M. (2023). Phytochemical Profile, Antilipase, Hemoglobin Antiglycation, Antihyperglycemic, and Anti-Inflammatory Activities of Solanum elaeagnifolium Cav. Applied Sciences, 13(20), 11519.

Darkwah, W. K., Koomson, D. A., Miwornunyuie, N., Nkoom, M., & Puplampu, J. B. (2020). Review: Phytochemistry and medicinal properties of Solanum torvum fruits. All Life, 13(1), 498–506.

Ditjen, P. O. M. (1985). Formularium kosmetika indonesia. Jakarta: Departemen Kesehatan RI. Hal, 83(85), 106–132.

Fitri, R., Syahputra, H. D., Nasri, N., Kaban, V. E., & Rani, Z. (2022). FORMULATION OF A BIOCELLULOSE MASK CONTAINING THE ESSENCE OF ALOE VERA (L.) BURM. F COMBINATION WITH VITAMIN E AS ANTI-AGING. ScienceRise: Pharmaceutical Science, 40(6).

Garg, A., Aggarwal, D., Garg, S., & Sigla, A. K. (2002). Spreading of Semisolid Formulation: An Update, Pharmaceutical Tecnology, September 2002, 84-102.

Helen, I., Hadinoto, I., Hadisoewignyo, L., & Soegianto, L. (2011). Effect of various concentration of vegetable protein in hair mask on the hair texture. Indonesian Journal of Cancer Chemoprevention, 2(1), 159–168.

Hidayat, D. H. Z., Fahmi, A. M., Mubiyna, F., Suri, C. A. M. P., Bagaskara, M., & Maharani, A. F. (2024). The Effect Of Natural Dye Extract From Beetroot (Beta Vulgaris L.) On The Quality Of Lip Tint Cosmetic Products. Jurnal EduHealth, 15(01), 730–734.

Indonesia, S. N. (2006). Petunjuk pengujian organoleptik dan atau sensori. Badan Standar Nasional. .

Kaba, B., Zannou, O., Ali Redha, A., & Koca, I. (2024). Enhancing extraction of betalains from beetroot (Beta vulgaris L.) using deep eutectic solvents: Optimization, bioaccessibility and stability. Food Production, Processing and Nutrition, 6(1), 38.

Kumar, L., Chadha, M., Rana, R., Kukreti, G., Kaundal, A. K., Aggarwal, V., & Vij, M. (2024). Polymeric microsponges: An emerging prospect in topical delivery of therapeutic agents. International Journal of Polymeric Materials and Polymeric Biomaterials, 73(11), 1003–1019.

Murrukmihadi, M. (2017). Pengaruh Penambahan Carbomer 934 Dan Setil Alkoholsebagai Emulgator Dalam Sediaan Krim Ekstrak Etanolik Bunga Kembang Sepatu (Hibiscus Rosa-sinenis L.) Terhadap Sifat Fisik Dan Aktivitas Antibakteri Pada Staphylococcus Aureus. Indonesia Natural Research Pharmaceutical Journal, 2(2), 131–140.

Ningtias, A., & Rani, Z. (2022). Formulasi Sediaan Pewarna Pipi dalam Bentuk Padat dengan Menggunakan Ekstrak Buah Buni (Antidesma bunius (L.) Spreng). INSOLOGI: Jurnal Sains Dan Teknologi, 1(4), 448–460.

Nurhikma, E., Antari, D., & Tee, S. A. (2018). Formulasi Sampo Antiketombe Dari Ekstrak Kubis (Brassica oleracea Var. Capitata L.) Kombinasi Ekstrak Daun Pandan Wangi (Pandanus amaryllifolius Roxb). Jurnal Mandala Pharmacon Indonesia, 4(1), 61–67.

Odoh, U., Ezugwu, C., & Okoro, E. (2012). Quantitative phytochemical, proximate/nutritive composition analysis of Beta Vulgaris Linnaeus (Chenopodiceae). Planta Medica, 78(11), s-0032-1320803. https://doi.org/10.1055/s-0032-1320803

Parmadi, A., & Pratama, B. (2020). Uji Efektivitas Krim Ekstrak Etanol Daun Iler (Coleusatropurpureusl. Benth) Terhadap Penyembuhan Luka Pada Mencit.

Patil, A., Bhide, S., Bookwala, M., Soneta, B., Shankar, V., Almotairy, A., Almutairi, M., & Narasimha Murthy, S. (2018). Stability of Organoleptic Agents in Pharmaceuticals and Cosmetics. AAPS PharmSciTech, 19(1), 36–47. https://doi.org/10.1208/s12249-017-0866-2

Rao, R. K. (2006). Food security.

Rowe, R. C., Sheskey, P., & Quinn, M. (2009). Handbook of pharmaceutical excipients. Libros Digitales-Pharmaceutical Press.

Sari, W. P., Gaya, M. L., Irianto, G., & Karima, N. (2019). Managemen Topikal Anti-Aging pada Kulit. Medical Profession Journal of Lampung, 9(2), 228–234.

Sayuti, N. A. (2016). Aktivitas Penumbuh Rambut Mikroemulsi Kombinasi Ekstrak Daun Waru (Hibiscus tiliaceus L) dan Asam Jawa (Tamarindus indica L). Prosiding Nasional APIKES-AKBID Citra Medika Surakarta, 1(1), 29–39.

Shapiro, J., Sicco, K. L., Otberg, N., Cummins, D., & Tuan, H.-H. (2024). Hair loss and restoration. CRC Press. Singh, R. K., Ruj, B., Sadhukhan, A. K., & Gupta, P. (2019). Thermal degradation of waste plastics under non-sweeping atmosphere: Part 1: Effect of temperature, product optimization, and degradation mechanism. Journal of Environmental Management, 239, 395–406.

Stefanov, S. R., & Andonova, V. Y. (2021). Lipid nanoparticulate drug delivery systems: Recent advances in the treatment of skin disorders. Pharmaceuticals, 14(11), 1083.

Sutriningsih, S., Sagala, Z., & Meliana, M. (2017). Uji Efektivitas Dan Uji Iritasi Gel Pewarna Rambut Dari Ekstrak Biji Buah Pepaya (Carica papaya L). Jurnal Muara Sains, Teknologi, Kedokteran Dan Ilmu Kesehatan, 1(1), 59–66.

Tranggono, I. R., & Latifah, F. (2014). Buku Pegangan Dasar Kosmetologi: Kosmetik Dekoratif. Jakarta: PT. Gramedia Pustaka Utama.

Walker, A. P., Basketter, D. A., Baverel, M., Diembeck, W., Matthies, W., Mougin, D., Röthlisberger, R., & Coroama, M. (1997). Test guidelines for the assessment of skin tolerance of potentially irritant cosmetic ingredients in man. Food and Chemical Toxicology, 35(10–11), 1099–1106.

Wang, S., Kang, Y., Qi, F., & Jin, H. (2023). Genetics of hair graying with age. Ageing Research Reviews, 89, 101977.

Wardiyah. (2016). Kimia Organik. In Pusat Pendidikan Sumber Daya Manusia Kesehatan. Kementerian Kesehatan Republik Indonesia Jakarta.


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Submitted: 2025-01-09
Published: 2025-02-28
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