Korelasi Efek Samping Obat Anti Tuberkulosis dengan Kepatuhan Pengobatan Pasien TB Paru
-
Sethiana Dewi Ruben
*
Poltekkes Kemenkes Jayapura, Papua,
Indonesia
- Santalia Banne Tondok Poltekkes Kemenkes Jayapura, Papua, Indonesia
- Guruh Suprayitno Poltekkes Kemenkes Jayapura, Papua, Indonesia (*) Corresponding Author
Abstract
Pulmonary TB is an infectious disease which is a major problem for health in communities, especially in developing countries. The incidence of TB in Indonesia in 2020 is 301 per 100,000 population, the death rate is 34 per 100,000 population. Pulmonary TB patients who do not comply with taking medication can cause a decrease in the cure rate and an increase in the death rate. OAT side effects are one of the causes of non-compliance. This study aims to determine the correlation of OAT side effects with adherence in pulmonary TB patients. The research design was an analytic observational cross sectional study approach and was carried out at the Asolokobal Health Center with a total sample of 30 respondents. Respondents filled out a questionnaire and gave a checklist on the perceived side effects of OAT, compliance was measured with the Guttman scale, the answers "Yes" or "No". The statistical test used is Chi Square with the alternative Fisher's Exact Test. The results of the study showed that 20 respondents (66.7%) adhered to the level of compliance with mild drug side effects. The level of compliance of respondents with symptoms of severe side effects who adhered to it was 6 respondents (20.0%), the level of compliance of respondents with symptoms of severe side effects who did not comply was 4 respondents (13.3%). Fisher's Exact Test, obtained p value = 0.008. It was concluded that there is a correlation between the side effects of anti-tuberculosis drugs and adherence to treatment of pulmonary TB patients.
Downloads
References
Abbas, A. (2017). Monitoring Of Side Effects Of Anti-Tuberculosis Drugs (ATD) On The Intensive Phase Treatment Of Pulmonary TB Patients In Makassar. Journal of Agromedicine and Medical Sciences, 3(1), 19. https://doi.org/10.19184/ams.v3i1.4093
Adam, L. (2020). Pengetahuan Penderita Tuberkulosis Paru Terhadap Kepatuhan Minum Obat Anti Tuberkulosis. Jambura Health and Sport Journal, 2(1), 12–18. https://doi.org/10.37311/jhsj.v2i1.4560
Afilla Christy, B., & Susanti, R. (2022). Hubungan Tingkat Kepatuhan Minum Obat Pasien Tuberkulosis Terhadap Efek Samping Obat Anti Tuberkulosis (OAT). Journal Syifa Sciences and Clinical Research, 4 No.2. https://doi.org/10.37311/jsscr.v4i2.14830
Ali, S. M., Kandaou, G. D., & Kaunang, W. P. J. (2019). Faktor - Faktor yang Berhubungan dengan Kepatuhan Berobat Penderita TB Paru di Wilayah Kerja Puskesmas Siko Kota Ternate. Stikes Graha Medika Nursing Journals, 2(1), 1–10.
Amsari, A. A., Handayani, R. R. D., & Tampubolon, E. H. (2019). Gambaran kontak serumah pasien tuberkulosis paru resisten obat dan faktor yang mempengaruhinya di RSUD kabupaten Sorong. http://repository.unipa.ac.id:8080/xmlui/handle/123456789/500
Anisa Rahayu Eka Putri, & Suwendar. (2022). Monitoring Efek Samping Obat Antituberkulosis (OAT) pada Pasien Tuberkulosis Kategori I di UPT Puskesmas Bayongbong Kabupaten Garut. Bandung Conference Series: Pharmacy, 2(2), 409–417. https://doi.org/10.29313/bcsp.v2i2.4231
Asriati, A., Alifariki, L. O., & Kusnan, A. (2019). Faktor Risiko Efek Samping Obat dan Merasa Sehat Terhadap Ketidakpatuhan Pengobatan Penderita Tuberkulosis Paru. JURNAL KESEHATAN PERINTIS (Perintis’s Health Journal), 6(2), 134–139. https://doi.org/10.33653/jkp.v6i2.344
Assosiated, F., Patiens, C., Tuberculosis, L., Swallowing, T., At, D., Sehat, R., Hospital, T., & Wulandari, D. H. (2015). Analisis Faktor-Faktor yang Berhubungan dengan Kepatuhan Pasien Tuberkulosis Paru Tahap Lanjutan Untuk Minum Obat di RS Rumah Sehat Terpadu Tahun 2015. Jurnal Administrasi Rumah Sakit Indonesia, 2(1), 17–28. https://doi.org/10.7454/arsi.v2i1.2186
Chen, X., Du, L., Wu, R., Xu, J., Ji, H., Zhang, Y., Zhu, X., & Zhou, L. (2020). The effects of family, society and national policy support on treatment adherence among newly diagnosed tuberculosis patients: A cross-sectional study. BMC Infectious Diseases, 20(1), 1–11. https://doi.org/10.1186/s12879-020-05354-3
Christy, B. A., Susanti, R., & Nurmainah. (2022). Hubungan Tingkat Kepatuhan Minum Obat Pasien Tuberkulosis Terhadap Efek Samping Obat Anti Tuberkulosis ( OAT ). Journal Syifa Sciences and Clinical Research, 4(2), 484–493.
Dasopang, E. S., Hasanah, F., Nisak, C., & Tjut. (2019). Analisis Deskriptif Efek Samping Penggunaan Obat Anti Tuberculosis pada Pasien TBC di RSUD Dr. Pirngadi Medan. Jurnal Penelitian Farmasi Herbal, 2(1), 44–49.
Ernawatyningsih, E., Purwanta, & Subekti, H. (2009). Faktor-Faktor Yang Mempengaruhi Ketidakpatuhan Berobat pada Penderita Tuberkulosis Paru (Factors Affecting Incompliance With Medication Among Lung Tuberculosis Patirnts). Berita Kedokteran Masyarakat, 25(3), 117–124.
Fitriani, D., Listiana, I., Pratiwi, R. D., & Mulia, M. (2021). Korelasi Perilaku Kesehatan Dan Efek Samping Oat Dengan Kepatuhan Penderita Tuberkulosis Paru Di Puskesmas Keranggan Tangerang Selatan. Edu Dharma Journal: Jurnal Penelitian Dan Pengabdian Masyarakat, 5(1), 97. https://doi.org/10.52031/edj.v5i1.98
Herawati, C., Nur Abdurakhman, R., Rundamintasih, N., & Studi Kesehatan Masyarakat Sekolah Tinggi Ilmu Kesehatan Cirebon, P. (2020). Peran Dukungan Keluarga, Petugas Kesehatan dan Perceived Stigma dalam Meningkatkan Kepatuhan Minum Obat pada Penderita Tuberculosis Paru. Jurnal Kesehatan Masyarakat Indonesia, 15(1).
Hermayani, & Maran, P. W. B. (2023). Narrative Literature Review ( NLR ) Pneumonia Sebagai Suatu Masalah Kesehatan Pada Bayi. Jurnal Kesehatan Tropis Indonesia, 1(3), 1–6.
Hiswani. (2014). Tuberkulosis Merupakan Penyakit Infeksi Yang Masih Menjadi Masalah Kesehatan Masyarakat. In Jakarta, Salemba Medika.
Istyanto, F., & Virgianti, L. (2023). Manfaat Dan Potensi Puasa Dalam Mencegah Risiko Penyakit Tidak Menular Jurnal Kesehatan Tropis Indonesia. Jurnal Kesehatan Tropis Indonesia, 1(2).
Kementerian kesehatan RI. (2014). Pedoman Nasional Pengendalian Tuberkulosis.
Kementerian kesehatan RI. (2020). Pedoman Nasional Pelayanan Kedokteran Tata Laksana Tuberkulosis. In Jakarta.
Kementerian kesehatan RI. (2021). Profil Kesehatan Indonesia. In Kesehatan Indonesia. Jakarta.
Kondoy, P. P. H., Rombot, D. V., Palandeng, H. M. F., & Pakasi, T. A. (2014). Faktor-Faktor Yang Berhubungan Dengan Kepatuhan Berobat Pasien Tuberkulosis Paru di Lima Puskesmas di Kota Manado. Jurnal Kedokteran Komunitas Dan Tropik, II, 1–8.
Marwansyah, M., & Sholikhah, H. H. (2016). The Infl uence of Empowering TB (Tuberculosis) Patients’ Family on Capability of Implementing The Family Health Task in Martapura and Astambul Public Health Center Areas in Banjar District. Buletin Penelitian Sistem Kesehatan, 18(4), 407–419. https://doi.org/10.22435/hsr.v18i4.4574.407-419
Prasetyo, M. . (2016). Pengaruh Terapi Suportif: Kelompok Terhadap Kepatuhan Minum Obat Klien TB Paru di Wilayah Puskesmas Patrang Kabupaten Jember. Universitas Negeri Jember.
Revision, F., Online, A., Phone, A., Tengah, D. B., Bcg, T., Tengah, D. B., & Tengah, D. B. (2022). ANALISIS FAKTOR KEJADIAN TB PARU DI KABUPATEN BUTON TENGAH Arimaswati*, Sukrianto Halik, Tety Yuniarty Sudiro, La Ode Kardin, Nina Indryani Nasruddin Jurusan Kedokteran, Fakultas Kedokteran, Universitas Halu Oleo, Indonesia. Jurnal Nursing Update, 13(1).
Rosadi, D. (2020). Faktor-Faktor yang Berhubungan dengan Kepatuhan Pasien Tuberkulosis Paru Terhadap Obat Anti Tuberkulosis. Jurnal Berkala Kesehatan, 6(2), 80. https://doi.org/10.20527/jbk.v6i2.9452
Safira, A. R., & Nahdliyyah, A. I. (2017). PENATALAKSANAAN FISIOTERAPI PADA KONDISI TUBERKULOSIS PARU DENGAN MODALITAS INFRARED DAN ACTIVE CYCLE OF BREATHING TECHNIQUE (ACBT) DI BBKPM SURAKARTA.,. Pena Jurnal Ilmu Pengetahuan Dan Teknologi, 31(1).
Samory, U. S., Yunalia, E. M., Suharto, I. P. S., & Nurseskasatmata, S. (2022). Faktor-Faktor Yang Berhubungan Dengan Kepatuhan Pasien Terhadap Pengobatan Tuberkulosis Paru Di Puskesmas Urei-Faisei (URFAS). Indonesian Health Science Journal, 2(1), 37–45. https://doi.org/10.52298/ihsj.v2i1.25
Sari, I. D., Yuniar, Y., & Syaripuddin, M. (2014). Studi Monitoring Efek Samping Obat Antituberkulosis Fdc Kategori 1 Di Provinsi Banten Dan Provinsi Jawa Barat. Media Penelitian Dan Pengembangan Kesehatan, 24(1), 28–35. https://doi.org/10.22435/mpk.v24i1.3484.28-35
Senewa, Philipus, F. (2016). Faktor-Faktor Yang Mempengaruhi Kepatuhan Berobat Penderita Tuberkulosis Paru di Puskesmas Depok. Bul.Penel.Kesehatan,Vol.30,No.1:31-38, 1–23.
Seniantara, Gabrilinda, Yohana, Adang, Theresia, Ivana, I. K. (2018). Pengaruh Efek Samping Oat ( Obat Anti Tuberculosis ) Terhadap Kepatuhan Minum. Jurnal Keperawatan Suaka Insan (Jksi), 3(2), 1–12.
Tika Maelani dan, & Cahyati, widya hary. (2019). Karakteristik Penderita, Efek Samping Obat dan Putus Berobat Tuberkulosis Paru. Higeia Journal of Public Health Research and Development, 3(2), 227–238.
Ulfah, U., Windiyaningsih, C., Abidin, Z., & Murtiani, F. (2018). Faktor-Faktor yang Berhubungan dengan Kepatuhan Berobat Pada Penderita Tuberkulosis Paru. The Indonesian Journal of Infectious Diseases, 4(1). https://doi.org/10.32667/ijid.v4i1.44
Ulfah, Windiyaningsih, C., Abidin, Z., & Murtiani, F. (2017). Faktor-Faktor yang Berhubungan dengan Kepatuhan Berobat Pada Penderita Tuberkulosis Paru Factors Related to Medication Adherence in Pulmonary Tuberculosis Patients. The Indonesian Journal of Infectious Diseases, 4(1).
Yuniar, I., & Lestari, S. D. (2017). Hubungan Status Gizi Dan Pendapatan Terhadap Kejadian Tuberkulosis Paru. Jurnal Perawat Indonesia, 1(1), 18. https://doi.org/10.32584/jpi.v1i1.5
Bila bermanfaat silahkan share artikel ini
Berikan Komentar Anda terhadap artikel Korelasi Efek Samping Obat Anti Tuberkulosis dengan Kepatuhan Pengobatan Pasien TB Paru
Pages: 413-420
Copyright (c) 2023 Sethiana Dewi Ruben, Santalia Banne Tondok, Guruh Suprayitno
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under Creative Commons Attribution 4.0 International License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (Refer to The Effect of Open Access).
