Uji Efektivitas Antidiabetes Rebusan Daun Belimbing Wuluh (Averrhoa bilimbi L.) pada Mencit (Mus musculus)
-
Washliaty Sirajuddin
*
ITKeS Muhammadiyah Sidrap, Sulawesi Selatan,
Indonesia
- Shabran Hadiq ITKeS Muhammadiyah Sidrap, Sulawesi Selatan, Indonesia
- Rahmatullah Rahmatullah ITKeS Muhammadiyah Sidrap, Sulawesi Selatan, Indonesia (*) Corresponding Author
Abstract
Diabetes mellitus is a condition where blood glucose levels increase due to the body's metaboIism of protein, fat, and carbohydrates. The purpose of this study was to determine the antidiabetic effectiveness of star fruit leaf decoction (Averrhoa bilimbi L.) on mice (Mus musculus). This type of research is a laboratory experimental study using 15 male mice divided into 5 groups of mice, each of which is fed for ± 8 hours. Then, the blood glucose level of mice was measured after being fed. Then, a glucose solution of 0.195 mg/0.2 ml was given. Next, blood glucose was measured, if each group of mice had experienced an increase in blood glucose levels, then given a negative control solution, positive control, and 10%, 15% and 20% decoction of starfruit leaves. Then measured the glucose levels of mice using a glucometer at 30, 60, and 90 minutes. The results showed that giving a 20% concentration of star fruit leaf (Averrhoa bilimbi L) decoction was effective as an antidiabetic with a percentage reduction of 42% in mice (Mus musculus).
Downloads
References
Agustin, M. J., Usman, U., & Umar, F. (2022). Aspek Sosial Budaya Terhadap Risiko Diabetes Mellitus pada Banyak Ketua Adat Tolotang (UWA) di Kabupaten Sidrap. Indonesian Health Journal, 1(2), 67–73. https://doi.org/10.58344/ihj.v1i2.19
American Diabetes Association (ADA). (2021). 2. Classification and diagnosis of diabetes: Standards of medical care in diabetes-2021. Diabetes Care, 44, S15–S33. https://doi.org/10.2337/dc21-S002
Anggraini, R. B. and R. Nurvinanda. "Skrining K. T. H. K. D. D. M. D. D. C. A. K. Bangka. " J. K. P. K. M. (PKM) 3. 2 (2020): 346-351. (2020). Skrining Kesehatan Tentang Hipertensi, Kolestrol Dan Diabetes Militus Di Desa Cengkong Abang Kabupaten Bangka.
Hanni Endarini, L. (2016). Farmakognisi dan Fitokimia (hlm. 145–156).
Hasim, H., Arifin, Y. Y., Andrianto, D., & Faridah, D. N. (2019). Ekstrak Etanol Daun Belimbing Wuluh (Averrhoa bilimbi) sebagai Antioksidan dan Antiinflamasi. Jurnal Aplikasi Teknologi Pangan, 8(3), 86. https://doi.org/10.17728/jatp.4201
Hasma, Suryanita. R. D. M. C. E. L., (2020). Efektivitas Rebusan Daun Muntingia Calabura L Segar Dan Kering Sebagai Penurun Hiperglikemia Pada Mencit. Kesehatan Manarang, J., Jurusan, S. D., & STIKES Nani Hasanuddin Makassar, F.Volume 6, Nomor 2.
Internasional Diabetes Federation. (2021). IDF Diabetes Atlas 10th edition. www.diabetesatlas.org
Jade septhimoranie, D. A. vinsa cantya prakasita. (2022). Aktivitas Antibakteri Ekstrak Kulit Batang Belimbing Wuluh terhadap Escherichia coli Penyebab Diare. Bioeksperimen, no.2(2460–1365), 79–87.
Kardela, W., Bellatasie, R., Rahmidasari, A., Wahyuni, S., & Wahyuni, F. (2022). Penilaian Kualitas Hidup Terkait Kesehatan Pasien Diabetes Melitus Tipe 2 Di Puskesmas Andalas Kota Padang. Jurnal Farmasi Higea, 14(2). www.jurnalfarmasihigea.org
Katzung, G. B. (2004). Farmakologi Dasar dan Klinik. Dalam Bagian Farmakologi Fakultas Kedokteran Universitas Erlangga (Ed.), 3 (8 ed.). Salemba Medika.
Lestari, Zulkarnain, & Sijid, ST. A. (2021). Diabetes Melitus: Review Etiologi. http://journal.uin-alauddin.ac.id/index.php/psb
Masaenah1, E., Rizky, F., 1program, A., Farmasi, S., Tinggi, S., Industri, T., & Bogor, F. (2019). Aktivitas Ekstrak Etanol Buah Belimbing Wuluh (Averrhoa Bilimbi L) Terhadap Penurunan Kadar Glukosa Darah Mencit Jantan (Mus musculus). In Jurnal Farmamedika (Vol. 4, Issue 2).
Putu Ovy Darmayanti, N., Putu Rahayu Artini, N., & Yudhistira Budhi Setiawan, P. (2020). Uji Aktivitas Analgetik Ekstrak Etanol 96% Daun Belimbing Wuluh (Averrhoa Bilimbi L.) Dengan Metode Geliat Pada Mencit Putih (Mus Musculus L) Galur Swiss Webster.
Salsabila, D. M., Alifiani2, N., Islam2, N., Febriana2, S., & Nisa2, T. C. (2022). Aktivitas Antioksidan dan Total Flavonoid Es Krim Naga Merah dan Lidah Buaya Sebagai Nonfarmakoterapi Dmt2.
Santi, D. T., & Candra, A. (2023). Skrining Fitokimia Dan Karaktersitik Salep Daun Averrhoa bilimbi. https://journal.unhas.ac.id/index.php/bioma
Sovia, E., & Ratwita, W. (2015). Aktivitas Antidiabetes Ekstrak Daun Belimbing Wuluh (Averrhoa bilimbi L). Jurnal Farmasi Galenika, 2, 15–21.
Togobu, M. D. (2018). Gambaran Perilaku Masyarakat Adat Karampuang Dalam Mencari Pengobatan Dukun (Ma’sanro). Jurnal Kesehatan Masyarakat, 4(1), 16–32.
Trisnawati, S. K., & Setyorogo, S. (2013). Faktor Risiko Kejadian Diabetes Melitus Tipe II Di Puskesmas Kecamatan Cengkareng Jakarta Barat Tahun 2012. In Jurnal Ilmiah Kesehatan (Vol. 5, Issue 1).
Yanti, S., Program, Y. V., Farmasi, S., Sarjana, P., Aufa, S., & Padangsidimpuan, R. (2019). Skrining Fitokimia Ekstrak Daun Belimbing Wuluh ( Averrhoa Bilimbi ) (Vol. 4, Issue 2).
Bila bermanfaat silahkan share artikel ini
Berikan Komentar Anda terhadap artikel Uji Efektivitas Antidiabetes Rebusan Daun Belimbing Wuluh (Averrhoa bilimbi L.) pada Mencit (Mus musculus)
Pages: 349-355
Copyright (c) 2023 Washliaty Sirajuddin, Shabran Hadiq, Rahmatullah Rahmatullah
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under Creative Commons Attribution 4.0 International License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (Refer to The Effect of Open Access).
