Hypoglycemic Effect of Lesser Yam (DioscoreahispidaDennst) Extract on Hyperglycemic Rats in Postprandial Condition
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Ari Yuniastuti
*
Universitas Negeri Semarang, Semarang,
Indonesia
- Retno Sri Iswari University of Muhammadiyah Semarang, Semarang, Indonesia
- R Susanti Universitas Negeri Semarang, Semarang, Indonesia
- Yanuarita Tursinawati University of Muhammadiyah Semarang, Semarang, Indonesia (*) Corresponding Author
Abstract
Hyperglycemia is a condition when the blood glucose levels exceed normal levels. Hyperglycemia can lead to the occurrence of Diabetes Mellitus (DM). The use of natural ingridients in lowering blood glucose levels has been carried out. However, studies on the benefits of lesser yam (Dioscorea esculenta) in reducing blood glucose levels have never been reported. This research aims to analyze the effect of administration lesser yam extract to hyperglycemic rats. Data were collected using experimental laboratoris pre-post test randomized design. Data were analysed using analysis of variance one way statistical test and advanced Tukey. Lesser yam contains Inulin as PLA (Water Soluble Polysaccharide) which serves to inhibit gastric emptying thus it can help manage a diet of people with hyperglycemic. The results obtained by the control group (not given treatment) shows no change in fasting blood glucose levels intesting as well as post prandial. The administration of lesser yam extract affects blood glucose levels to decreased in hyperglycemic rats in all groups. Significant decrease occurs in the testing conditions of first, second and third day post prandial group. The decrease is caused by the influence of the extracts after 2 hours of administration. Lesser yam (DioscoreahispidaDennst) is capable of lowering blood glucose levels of hyperglycemic rats in post prandial condition.
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References
Adam, J. M. F., 2000, Klasifikasi dan Kriteria Diagnosis Diabetes Melitus yang Baru. Cermin Dunia Kedokteran, 127:37-40.
American Diabetes Association. 2016. Diagnosis and Classification of Diabetes Mellitus. Diabetes Care. 35(1): 64-71.
Aprianita, A., Purwandari, Watson and Vasiljevic. 2009. Physico-chemical properties of flours and starches from selected commercial tubers available in Australia. Int. Food Res. J. 16: 507-520.
Ardiansari, Y.M. 2012.Pengaruhjenisgadungdan lama perebusan terhadap kadar sianida gadung. Skripsi. Fakultas Kesehatan Masyarakat Universitas Jember.
Badan Standarisasi Nasional. 2006. SNI 01- 7152- 2006 Bahan tambahan pangan– Persyaratan perisa dan penggunaan dalam produk pangan. Jakarta. Badan Standarisasi Nasional.
Dewoto, H.R. 2007. Pengembangan obat tradisional Indonesia menjadi fitofarmaka. Majalah kedokteran Indonesia. 57(7): 205-211.
Harijono, Teti, E., Wenny, B.S., & Komang, I.S. 2012.Efek Hipoglikemik Polisakarida Larut Air Gembili (Dioscoreaesculanta) Yang Diekstrak Dengan Berbagai Metode. Jurnal Tekonologi dan Pangan. 23(1): 1-8.
Harijono, Estiasih T, Sunarharum WB, & Hartono MD. 2013. Hypoglycemic effect of biscuits containing water-soluble polysaccharides from wild yam (DioscoreahispidaDennts) or lesser yam (Dioscoreaesculenta) tubers and alginate. International Food Research Journal 20(5): 2279-2285.
Hikmah, N., Yuliet, and Khildah, K. 2016. Pengaruh Pemberian Ekstrak Daun Salam (SyzygiumPolyanthum Wight.) Terhadap Glibenklamid dalam Menurunkan Kadar GlukosaDarahMencit (MusMusculus) yang Diinduksi Alloxan. GALENIKA Journal of Pharmacy. 2(1): 24-30.
Janagam, R. D. Siddeswaran, and R. Kumar. 2008. The biochemical effects on occupational of workers to HCN on cassava processing industry. Indian J. of Science and Technology. 1(7): 1-4.
Li, F., Li, Q., Gao, D., and Peng, Y. 2009. The optimal Extraction Parameters and Antidiabetic Activity Of Flavonoids From Ipomea Batatas Leaf. Afr. J. Traditional. 6 (2): 195 – 202.
Lunn, J and Burrtiss, J.L. 2007.Carbohydrates and dietary fibre.Nutrition Bulletin. 32: 21-64.
Nugroho, A.E. 2006. Review Hewan Percobaan Diabetes Mellitus: Patologi Dan Mekanisme Aksi Diabetogenik. Biodiversitas. 7(4): 378-382.
Putri, N.H.K and Muhammad, A.I. 2013. Hubungan Empat Pilar Pengendalian DM Tipe 2 dengan Rerata Kadar Gula Darah. Jurnal Berkala Epidemiologi. 1(2): 234-243.
Rahmawati DA. 2010. Aktivitas Antihiperglikemik Dari Biomassa Dan Polisakarida Ekstraseluler Porphyridium Cruentum Sebagai Inhibitor Α-Glukosidase. Skripsi. Institut Pertanian Bogor: Bogor.
Saputro, P.S and Teti, E. 2015. Pengaruh Polisakarida Larut Air (PLA) dan Serat Pangan Umbi-Umbian Terhadap Glukosa Darah: Kajian Pustaka. Jurnal Pangandan Agroindustri. 3(2): 756-762.
Sunarsih, Endang S. D. and Retno, S. U. 2007. Pengaruh pemberian infusa umbi gadung (DioscoreahispidaDennst) terhadap penurunan kadar glukosa darah tikus putih jantan diabetes yang diinduksi alloxan. Majalah Farmasi Indonesia 18(1): 29-33.
Teti, E., Harijono, Weny, B.S. and Atina, R. 2012.Hypoglicemic of Yam (Dioscoreahispida Dents) Prepared by Aqueous, Papain, and Tempeh Inoculum Assisted Extractions. World Academy of Science, engineering and Technology. 6(10): 311-317.
Wikanta T, Rahma D and Lestari R. 2008.PengaruhPemberian Κ-Karagenan Dan Ί-Karagenan Terhadap Penurunan Kadar Glukosa Darah Tikus Hiperglikemia. Jurnal Pascapanen dan Bioteknologi Kelautan dan Perikanan. 3(2): 131-138.
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