Implementasi Transfer Learning pada Convolutional Neural Network dengan Arsitektur VGG dalam Klasifikasi Down Syndrome di Asia
Abstract
Early detection of Down syndrome is crucial for enabling early intervention and providing healthcare education for children. Down syndrome is associated with specific facial features, such as distinct characteristics of the eyes, nose, lips, face shape, hair, and skin color, which can be analyzed using computer vision techniques. This study aims to classify Down syndrome, especially in the Asian Region, which includes countries with medium/low SDI. The study proposed a CNN based on the VGG16 and VGG19 architectures by implementing transfer learning and augmentation. Augmentation is performed to balance the number of images between classes, while transfer learning is used to train the model first on ImageNet data. The dataset used consists of two categories, Down syndrome and Healthy. The results indicate that the VGG16 model has higher sensitivity and is able to classify more cases of Down syndrome, but has a fairly large prediction error. However, VGG19 model has a better specificity value and has a smaller potential for prediction error. The best model in this study was selected based on the highest validation accuracy value, where VGG19 achieved an accuracy of 93% in its best iteration, and VGG16 achieved an accuracy of 91%. These findings suggest that the proposed models, particularly VGG19, exhibit optimal performance in classifying Down syndrome, especially in the Asian region, with a lower prediction error rate.
Downloads
References
M. K. S. A. Dr. Roedi Irawan, Kelainan Genetik dan Diagnosis Sindrom Down. Surabaya: Airlangga University Press, 2021, ISBN: 978-602-473-759-7.
T. O. Natania, R. Larasati, and E. Purwaningsih, “SYSTEMATIC LITERATURE REVIEW: PEMELIHARAAN KESEHATAN GIGI DAN MULUT PENYANDANG DOWN SYNDROME DITINJAU DARI PERAN ORANG TUA,” Jurnal Kesehatan Gigi dan Mulut (JKGM), vol. 3, no. 2, pp. 47–54, Nov. 2021, doi: 10.36086/jkgm.v3i2.909.
S. N. Siti and S. Sudarman, “Hubungan antara Kemampuan Mengunyah Makanan dengan Kemampuan Artikulasi pada Anak Down Syndrome di Samarinda,” Jurnal Terapi Wicara dan Bahasa, vol. 1, no. 2, pp. 347–360, Jun. 2023, doi: 10.59686/jtwb.v1i2.39.
S. E. Antonarakis et al., “Down syndrome,” Nat Rev Dis Primers, vol. 6, no. 1, p. 9, Feb. 2020, doi: 10.1038/s41572-019-0143-7.
N. D. A. Lubis, H. Sasmita, S. Amelia, and A. Yosi, “Promoting Positive Deviance from PIK POTADS North Sumatra to Improve the Quality of Life of Down Syndrome Children,” ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat, vol. 8, no. 2, pp. 995–1000, Dec. 2023, doi: 10.32734/abdimastalenta.v8i2.11540.
L. Chen et al., “Global, Regional, and National Burden and Trends of Down Syndrome From 1990 to 2019,” Front Genet, vol. 13, no. July, pp. 1–14, Jul. 2022, doi: 10.3389/fgene.2022.908482.
S. Hussain et al., “Modern Diagnostic Imaging Technique Applications and Risk Factors in the Medical Field: A Review,” Biomed Res Int, vol. 2022, no. 1, p. 5164970, Jan. 2022, doi: 10.1155/2022/5164970.
N. A. Ujilast, N. S. Firdausita, C. S. K. Aditya, and Y. Azhar, “MRI Image Based Alzheimer’s Disease Classification Using Convolutional Neural Network: EfficientNet Architecture,” Jurnal RESTI (Rekayasa Sistem dan Teknologi Informasi), vol. 8, no. 1, pp. 18–25, Jan. 2024, doi: 10.29207/resti.v8i1.5457.
N. Paredes, E. Caicedo-Bravo, and B. Bacca, “Emotion Recognition in Individuals with Down Syndrome: A Convolutional Neural Network-Based Algorithm Proposal,” Symmetry (Basel), vol. 15, no. 7, p. 1435, Jul. 2023, doi: 10.3390/sym15071435.
F. F. Sherif, N. Tawfik, D. Mousa, M. S. Abdallah, and Y.-I. Cho, “Automated Multi-Class Facial Syndrome Classification Using Transfer Learning Techniques,” Bioengineering, vol. 11, no. 8, p. 827, Aug. 2024, doi: 10.3390/bioengineering11080827.
E. Setyati, S. Az, S. P. Hudiono, and F. Kurniawan, “CNN based Face Recognition System for Patients with Down and William Syndrome,” Knowledge Engineering and Data Science, vol. 4, no. 2, p. 138, Dec. 2021, doi: 10.17977/um018v4i22021p138-144.
M. D. A. Pranatha, G. H. Setiawan, and M. A. Maricar, “Utilization of ResNet Architecture and Transfer Learning Method in the Classification of Faces of Individuals with Down Syndrome,” Journal of Applied Informatics and Computing, vol. 8, no. 2, pp. 434–442, Nov. 2024, doi: 10.30871/jaic.v8i2.8474.
N. Paredes, E. F. Caicedo-Bravo, B. Bacca, and G. Olmedo, “Emotion Recognition of Down Syndrome People Based on the Evaluation of Artificial Intelligence and Statistical Analysis Methods,” Symmetry (Basel), vol. 14, no. 12, p. 2492, Nov. 2022, doi: 10.3390/sym14122492.
L. Alzubaidi et al., “Review of deep learning: concepts, CNN architectures, challenges, applications, future directions,” J Big Data, vol. 8, no. 1, p. 53, Mar. 2021, doi: 10.1186/s40537-021-00444-8.
K. Rezaee, “Machine learning and facial recognition for down syndrome detection: A comprehensive review,” Computers in Human Behavior Reports, vol. 17, p. 100600, Mar. 2025, doi: 10.1016/j.chbr.2025.100600.
Y. R., V. Raja Sarobin M., R. Panjanathan, G. J. S., and J. A. L., “Diabetic Retinopathy Classification Using CNN and Hybrid Deep Convolutional Neural Networks,” Symmetry (Basel), vol. 14, no. 9, p. 1932, Sep. 2022, doi: 10.3390/sym14091932.
W. Setiawan, “PERBANDINGAN ARSITEKTUR CONVOLUTIONAL NEURAL NETWORK UNTUK KLASIFIKASI FUNDUS,” Jurnal Simantec, vol. 7, no. 2, pp. 48–53, Jun. 2020, doi: 10.21107/simantec.v7i2.6551.
W. M. Pradnya D and A. P. Kusumaningtyas, “Analisis Pengaruh Data Augmentasi Pada Klasifikasi Bumbu Dapur Menggunakan Convolutional Neural Network,” JURNAL MEDIA INFORMATIKA BUDIDARMA, vol. 6, no. 4, p. 2022, Oct. 2022, doi: 10.30865/mib.v6i4.4201.
T. B. Sasongko, H. Haryoko, and A. Amrullah, “Analisis Efek Augmentasi Dataset dan Fine Tune pada Algoritma Pre-Trained Convolutional Neural Network (CNN),” Jurnal Teknologi Informasi dan Ilmu Komputer, vol. 10, no. 4, pp. 763–768, Aug. 2023, doi: 10.25126/jtiik.20241046583.
E. Rachmawati, N. A. Agustina, and F. Sthevanie, “Pengenalan Ras Berdasarkan Hidung Dan Mulut Menggunakan Gray Level Co-Occurrence Matrix,” Jurnal Teknologi Informasi dan Ilmu Komputer, vol. 8, no. 4, pp. 729–734, Jul. 2021, doi: 10.25126/jtiik.2021844366.
Y. N. FUADAH, I. D. UBAIDULLAH, N. IBRAHIM, F. F. TALININGSING, N. K. SY, and M. A. PRAMUDITHO, “Optimasi Convolutional Neural Network dan K-Fold Cross Validation pada Sistem Klasifikasi Glaukoma,” ELKOMIKA: Jurnal Teknik Energi Elektrik, Teknik Telekomunikasi, & Teknik Elektronika, vol. 10, no. 3, p. 728, Jul. 2022, doi: 10.26760/elkomika.v10i3.728.
W. Setiawan, Deep Learning menggunakan Convolutional Neural Network: Teori dan Aplikasi, Cetakan I. Malang: Media Nusa Creative (MNC Publishing), 2021, ISBN: 978-602-462-446-0.
B. Nugroho and E. Y. Puspaningrum, “Kinerja Metode CNN untuk Klasifikasi Pneumonia dengan Variasi Ukuran Citra Input,” Jurnal Teknologi Informasi dan Ilmu Komputer, vol. 8, no. 3, pp. 533–538, Jun. 2021, doi: 10.25126/jtiik.2021834515.
Weny Indah Kusumawati and Adisaputra Zidha Noorizki, “Perbandingan Performa Algoritma VGG16 Dan VGG19 Melalui Metode CNN Untuk Klasifikasi Varietas Beras,” Journal of Computer, Electronic, and Telecommunication, vol. 4, no. 2, Dec. 2023, doi: 10.52435/complete.v4i2.387.
T. A. R. Ramadhani and A. R. Manga, “Analisis Perbandingan VGG-16 dan ResNet50 untuk Klasifikasi Multilabel Gambar Kerbau Toraja: Pendekatan Deep Learning,” Jurnal Teknik, vol. 22, no. 2, pp. 71–81, Dec. 2024, doi: 10.37031/jt.v22i2.490.
M. K. Insani and D. B. Santoso, “Perbandingan Kinerja Model Pre-Trained CNN (VGG16, RESNET, dan INCEPTIONV3) untuk Aplikasi Pengenalan Wajah pada Sistem Absensi Karyawan,” Jurnal Indonesia : Manajemen Informatika dan Komunikasi, vol. 5, no. 3, pp. 2612–2622, Sep. 2024, doi: 10.35870/jimik.v5i3.925.
R. A. Mas’ud and Junta Zeniarja, “Optimasi Convolutional Neural Networks untuk Deteksi Kanker Payudara menggunakan Arsitektur DenseNet,” Edumatic: Jurnal Pendidikan Informatika, vol. 8, no. 1, pp. 310–318, Jun. 2024, doi: 10.29408/edumatic.v8i1.25883.
M. Diwakaran and D. Surendran, “Breast Cancer Prognosis Based on Transfer Learning Techniques in Deep Neural Networks,” Information Technology and Control, vol. 52, no. 2, pp. 381–396, Jul. 2023, doi: 10.5755/j01.itc.52.2.33208.
Bila bermanfaat silahkan share artikel ini
Berikan Komentar Anda terhadap artikel Implementasi Transfer Learning pada Convolutional Neural Network dengan Arsitektur VGG dalam Klasifikasi Down Syndrome di Asia
Pages: 21-31
Copyright (c) 2025 Tarissa Rizky Salsabiila Uwar, Christian Sri Kusuma Aditya

This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under Creative Commons Attribution 4.0 International License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (Refer to The Effect of Open Access).





















